Linagliptin-Associated Alopecia and Bullous Pemphigoid
September 2019
in “
European Journal of Case Reports in Internal Medicine
”
TLDR Linagliptin may cause hair loss and skin blisters.
A 68-year-old man with type 2 diabetes developed alopecia and bullous pemphigoid after starting linagliptin, a DPP-4 inhibitor. Skin biopsies confirmed bullous pemphigoid, and discontinuing linagliptin, along with treatment, led to significant improvement within 6 months. This case suggested a potential link between linagliptin and these dermatological side effects, emphasizing the importance of monitoring and early diagnosis in patients on this medication.