Linagliptin-Associated Alopecia and Bullous Pemphigoid

A 68-year-old man with type 2 diabetes developed diffuse alopecia and bullous pemphigoid (BP) a few months after starting linagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor. This case was notable as it was the first reported instance of linagliptin being associated with both alopecia areata and BP. The findings suggested a potential link between DPP-4 inhibitors and alopecia, emphasizing the need for early diagnosis and the significant impact of discontinuing the DPP-4 inhibitor on disease remission.