Linagliptin-Associated Alopecia and Bullous Pemphigoid

    Ali Someili, Mohannad Abu‐Hilal, Khalid Azzam
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    Studysummary This case report describes a 68-year-old man who developed both alopecia areata and bullous pemphigoid after starting linagliptin for diabetes, suggesting a possible link with DPP-4 inhibitors.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A 68-year-old man with type 2 diabetes developed alopecia and bullous pemphigoid after starting linagliptin, a DPP-4 inhibitor. Skin biopsies confirmed bullous pemphigoid, and discontinuing linagliptin, along with treatment, led to significant improvement within 6 months. This case suggested a potential link between linagliptin and these dermatological side effects, emphasizing the importance of monitoring and early diagnosis in patients on this medication.
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