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    Glossary Dipeptidyl Peptidase-4

    enzyme that breaks down incretin hormones, regulating insulin levels

    Dipeptidyl Peptidase-4 (DPP-4) is an enzyme that plays a role in glucose metabolism by breaking down incretin hormones, which help regulate insulin levels in the body. It is also known as CD26 and is involved in immune system functions. Inhibitors of DPP-4 are used in the treatment of type 2 diabetes to improve blood sugar control.

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    Research 10 of 252

    1. Inhibiting dipeptidyl peptidase 4 positive fibroblasts using zinc sulfide cellulose nanofiber scaffolds to achieve scarless healing International Journal of Biological Macromolecules · 2024 · 4 citations
    2. 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin Journal of Investigative Dermatology · 2019
    3. 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor Journal of Investigative Dermatology · 2016
    4. Linagliptin-Associated Alopecia and Bullous Pemphigoid European Journal of Case Reports in Internal Medicine · 2019 · 7 citations
    5. Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration Journal of Investigative Dermatology · 2023
    6. 613 Bacteria induce skin regeneration via IL-1β signaling Journal of Investigative Dermatology · 2021
    7. 612 Wnt signaling induces fibrotic fat loss via DPP4 in skin fibrosis Journal of Investigative Dermatology · 2021
    8. 1434 Role of fibroblast DPP4 in wound healing, scarring and regeneration Journal of Investigative Dermatology · 2018
    9. Cardiovascular profile of pharmacological agents used for the management of polycystic ovary syndrome Therapeutic Advances in Endocrinology and Metabolism · 2019 · 4 citations
    10. 362 Not just a cell marker: DPP4 modulates regeneration of hair follicles in large wounds Journal of Investigative Dermatology · 2021
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