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GlossaryDipeptidyl Peptidase-4

enzyme that breaks down incretin hormones, regulating insulin levels

Dipeptidyl Peptidase-4 (DPP-4) is an enzyme that plays a role in glucose metabolism by breaking down incretin hormones, which help regulate insulin levels in the body. It is also known as CD26 and is involved in immune system functions. Inhibitors of DPP-4 are used in the treatment of type 2 diabetes to improve blood sugar control.

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Dipeptidyl Peptidase-4 Inhibitors

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research Dipeptidyl-Peptidase 4 (DPP4)-Positive Fibroblasts Are Responsible for Secretion of Pro-Fibrotic Matrix Proteins in Human Skin

April 2019 in “Journal of Investigative Dermatology”

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

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