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    Glossary Dipeptidyl Peptidase-4 Inhibitors

    block the enzyme DPP-4 to help regulate blood sugar

    Dipeptidyl Peptidase-4 Inhibitors, often abbreviated as DPP-4 inhibitors, are a class of oral medications used to manage type 2 diabetes. They work by blocking the enzyme DPP-4, which results in increased levels of incretin hormones. These hormones help to regulate blood sugar by increasing insulin release and decreasing glucagon levels, particularly after meals.

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    Research 30 of 238

    1. 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor Journal of Investigative Dermatology · 2016
    2. Inhibiting dipeptidyl peptidase 4 positive fibroblasts using zinc sulfide cellulose nanofiber scaffolds to achieve scarless healing International Journal of Biological Macromolecules · 2024 · 4 citations
    3. 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin Journal of Investigative Dermatology · 2019
    4. Linagliptin-Associated Alopecia and Bullous Pemphigoid European Journal of Case Reports in Internal Medicine · 2019 · 7 citations
    5. Cardiovascular profile of pharmacological agents used for the management of polycystic ovary syndrome Therapeutic Advances in Endocrinology and Metabolism · 2019 · 4 citations
    6. 613 Bacteria induce skin regeneration via IL-1β signaling Journal of Investigative Dermatology · 2021
    7. 612 Wnt signaling induces fibrotic fat loss via DPP4 in skin fibrosis Journal of Investigative Dermatology · 2021
    8. Alopecia areata universalis nach Sitagliptin-Einnahme ˜Derœ Hautarzt · 2020 · 2 citations
    9. Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration Journal of Investigative Dermatology · 2023
    10. Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase Molecules · 2015 · 25 citations
    11. Antidiabetic Management Strategies for Treatment of Polycystic Ovarian Syndrome Journal of Neonatal Surgery · 2025
    12. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis Journal of Advanced Research · 2024 · 8 citations
    13. DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho−/− mice Cardiovascular diabetology · 2017 · 20 citations
    14. Women With Polycystic Ovary Syndrome: A Review of Susceptibility to Type 2 Diabetes Cureus · 2023
    15. The compatibility of Bacillus thuringiensis Cry protein-solubilizing buffers with the droplet feeding method in fall armyworm larvae Journal of Invertebrate Pathology · 2019
    16. Risk of Suicide, Hair Loss, and Aspiration with GLP1-Receptor Agonists and Other Diabetic Agents: A Real-World Pharmacovigilance Study Cardiovascular Drugs and Therapy · 2024 · 25 citations
    17. Short Peptides Induce Development of Root Hair Nicotiana tabacum Plants · 2022
    18. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/β-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    19. Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands# Medicinal Chemistry · 2018 · 16 citations
    20. Distinct Conditions Support a Novel Classification for Bradykinin-Mediated Angio-Oedema Dermatology · 2015 · 11 citations
    21. Author response: Structural basis of malodour precursor transport in the human axilla 2018 · 1 citations
    22. Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique NPJ breast cancer · 2024 · 1 citations
    23. CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation Journal of Cellular and Molecular Medicine · 2025 · 3 citations
    24. The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring Pharmaceutics · 2023 · 1 citations
    25. Reversing Time with Peptides: Mechanisms, Classifications, and Innovations in Anti-aging Interventions Commagene Journal of Biology · 2026
    26. The Current Status of the Pharmaceutical Potential of Juniperus L. Metabolites Medicines · 2018 · 19 citations
    27. Benefit-Risk Assessment of GLP-1 Receptor Agonists: Implications for Dermatologists and Plastic Surgeons Dermatology and Therapy · 2025 · 1 citations
    28. Hair Loss in Patients on Glucagon-Like Peptide 1 Receptor Agonists: Understanding Risks and Managing Outcomes Dermatology and Therapy · 2026
    29. Pre-clinical non-viral vectors exploited for<i>in vivo</i>CRISPR/Cas9 gene editing: an overview Biomaterials Science · 2022 · 23 citations
    30. Farmácia Azevedo Carvalho, Cabeceiras de Bastos Open Repository of the University of Porto (University of Porto) · 2023