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    Glossary PADI4

    enzyme that converts arginine residues into citrulline in proteins

    PADI4, also known as Peptidylarginine Deiminase 4, is an enzyme that plays a role in the modification of proteins by converting arginine residues into citrulline in a process called citrullination. This enzyme is involved in various biological processes, including gene regulation and the immune response, and has been implicated in autoimmune diseases such as rheumatoid arthritis.

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    Research 10 of 546

    1. A Hairy Cituation – PADIs in Regeneration and Alopecia Frontiers in Cell and Developmental Biology · 2021 · 5 citations
    2. Co-expression of PADI isoforms during progenitor differentiation enables functional diversity Philosophical Transactions of the Royal Society B Biological Sciences · 2023 · 2 citations
    3. The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles Science Advances · 2025
    4. Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome American journal of human genetics · 2016 · 119 citations
    5. Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles BMC Dermatology · 2020 · 4 citations
    6. Variant <i>PADI3</i> in Central Centrifugal Cicatricial Alopecia The New England Journal of Medicine · 2019 · 95 citations
    7. Reciprocal role of vitamin D receptor on β-catenin regulated keratinocyte proliferation and differentiation The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 49 citations
    8. Skin transcriptome profiling of Changthangi goats highlights the relevance of genes involved in Pashmina production Scientific reports · 2020 · 22 citations
    9. Genetic Susceptibility to Alopecia The New England Journal of Medicine · 2019 · 5 citations
    10. Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles Biological & pharmaceutical bulletin · 2017 · 4 citations
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