Alopecia Universalis After Sitagliptin Intake

November 2020 in “ Der Hautarzt ”

Johannes Kohlmann, Rubén A. Ferrer, Aleksander Markovic, Monica Illes, Manfred Kunz

alopecia areata universalis Sitagliptin Dipeptidylpeptidase-4 inhibitor DPP-4 inhibitor Metformin Dapagliflozin immunological interaction immune system alopecia hair loss diabetes medication

Studysummary This case report suggests an association between the use of Sitagliptin, a DPP-4 inhibitor, and the development of alopecia universalis in a diabetic patient.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.

research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity

717 citations , June 2010 in “Nature”

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research Acute Alopecia Due to Metformin Treatment for Polycystic Ovarian Syndrome

5 citations , January 2006 in “Journal of obstetrics and gynaecology”

Metformin can cause hair loss in some women with PCOS.