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Glossary Alopecia Universalis

complete loss of all body and scalp hair

Alopecia Universalis (AU) is a severe form of alopecia areata characterized by the complete loss of hair on the scalp and body, including eyebrows and eyelashes. It is an autoimmune condition where the immune system mistakenly attacks hair follicles, leading to total hair loss.

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Research

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research PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology

105 citations , December 1995 in “British journal of dermatology/British journal of dermatology, Supplement”

This retrospective study concluded that PUVA treatment is generally ineffective for alopecia areata, with low effective success rates for partialis, totalis, and universalis types.

research Development of Alopecia Areata Universalis in a Patient Receiving Adalimumab

69 citations , December 2006 in “Archives of dermatology”

This entry contains no research abstract, so no scientific findings or conclusions are reported.

research Latanoprost in the treatment of eyelash alopecia in alopecia areata universalis

50 citations , December 2009 in “Journal of The European Academy of Dermatology and Venereology”

This study found that latanoprost may be effective for treating eyelash alopecia areata, achieving cosmetically acceptable regrowth in 45% of patients.

research Transient Efficacy of Tofacitinib in Alopecia Areata Universalis

39 citations , April 2016 in “Case Reports in Dermatology”

This study observed initial hair regrowth in a businessman with alopecia areata universalis treated with tofacitinib, but the effect diminished, leading to renewed hair loss.

research PUVA treatment of alopecia areata totalis and universalis: A retrospective study

39 citations , April 2003 in “Australasian journal of dermatology”

This study found that PUVA treatment resulted in complete hair regrowth in over half of patients with alopecia areata totalis or universalis, despite a higher treatment failure rate in those with a family history of the condition.

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Community Join

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community Alopecia Areata Question

2 upvotes 5 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community Xeljanz medication for alopecia universalis?

4 upvotes 2 months ago

A person with alopecia universalis is considering using Xeljanz but is advised that Olumiant is more effective for their condition. They are under a dermatologist's care and should expect gradual progress, as follicles dormant for 20 years are challenging to reactivate.

community Drug restored full hair in 23% and over 80% of hair in 55% in 6 months

240 upvotes 2 weeks ago

An arthritis drug restored significant hair in people with alopecia areata, but it is not effective for male pattern baldness. The drug, Upadacitinib, has serious side effects and is expensive.

community Hairloss all over body and head

4 upvotes 8 months ago

A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

community 30 Female, a month into 5% Minoxidil - is this normal?

28 upvotes 1 year ago

A 30-year-old woman experiencing rapid hair loss is using 5% Minoxidil, Saw Palmetto, vitamins, and Nizoral, but is advised to see a dermatologist as her symptoms may indicate a condition other than androgenetic alopecia, such as alopecia areata or a thyroid issue. Many suggest a biopsy and blood tests to determine the underlying cause.

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Learn

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learn Scalp Micropigmentation

Is scalp micropigmentation suitable for all types of hair loss? Scalp micropigmentation is generally suitable for various types of hair loss.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

learn Bimatoprost

Is bimatoprost effective for people with alopecia areata? Bimatoprost may stimulate hair growth but lacks strong evidence for alopecia areata.

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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