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GlossaryGLP-1 receptor agonists

mimic a hormone to regulate blood sugar and promote fullness

GLP-1 receptor agonists are a class of medications that mimic the action of the glucagon-like peptide-1 (GLP-1) hormone, which helps regulate blood sugar levels by enhancing insulin secretion and inhibiting glucagon release. They are commonly used in the treatment of type 2 diabetes and can also promote weight loss by slowing gastric emptying and increasing feelings of fullness.

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research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects

59 citations, August 2021 in “Frontiers in Endocrinology”

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

research Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review

February 2025 in “Skin Appendage Disorders”

GLP-1 receptor agonists can cause skin reactions, facial fat loss, and hair loss, but may help with wound healing and skin conditions.

From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services

research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services

August 2024 in “Nutrition Bulletin”

GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.

research Risk of Alopecia Areata with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss

February 2025 in “medRxiv (Cold Spring Harbor Laboratory)”

GLP-1 agonists may increase the risk of hair loss.

research GLP-1 RAs and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions

June 2025

GLP-1 receptor agonists can cause skin and hair issues due to rapid weight loss, but these can be managed with proper care and treatments.

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community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 54 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community The end of balding: We may have just found the secret to hair regrowth

in Technology 679 upvotes 2 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.

community He used Dutasteride for 20 years. Interview

in Treatment 111 upvotes 7 months ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

community Any treatments in development that could theoretically give complete regrowth?

in Research/Science 7 upvotes 1 month ago

New hair loss treatments like PP-405, AMP-303, and SCUBE3 are being discussed, but none are confirmed to fully restore hairlines. Current treatments like Minoxidil, Finasteride, and RU58841 are still widely used, with some hope for future advancements in hair regrowth.

community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 6 months ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

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