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GlossaryGlucagon-Like Peptide-1 (GLP-1)

hormone that regulates blood sugar and promotes fullness

Glucagon-Like Peptide-1 (GLP-1) is a hormone produced in the gut that plays a crucial role in regulating blood sugar levels by enhancing insulin secretion and inhibiting glucagon release after eating. It also slows gastric emptying and promotes a feeling of fullness, making it a target for treatments in type 2 diabetes and obesity.

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research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects

59 citations, August 2021 in “Frontiers in Endocrinology”

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

research GLP-1 Agonists and Hair Loss: A Call for Further Investigation

May 2024 in “International Journal of Dermatology”

More research is needed to understand if GLP-1 agonists affect hair health.

From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services

research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services

August 2024 in “Nutrition Bulletin”

GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.

research Glucagon-Like Peptide-1 Receptor and Proglucagon Expression in Mouse Skin

37 citations, March 2006 in “Regulatory Peptides”

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

research Ann Robinson’s Research Reviews — 12 May 2022

May 2022 in “The BMJ”

Self-monitoring blood pressure in pregnant women didn't improve outcomes, diabetes drugs may increase gallbladder disease risk, a new drug helps severe hair loss, a plant-based COVID-19 vaccine is 69.5% effective, and new anticoagulants are safer for diabetics with heart rhythm issues than warfarin.

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community Wtf have we been doing for the last 30 years

in Treatment 526 upvotes 4 days ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 1 year ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 53 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community He used Dutasteride for 20 years. Interview

in Treatment 109 upvotes 1 month ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.