37 citations
,
February 2023 in “Gut Microbes” This study found that administering the gut bacterium Thauera sp. strain GDN1 to mice significantly reduced their serum androgen levels, indicating gut bacteria may influence androgen metabolism.
16 citations
,
January 2021 in “Dermatology and therapy” This review discusses the role of gut microbiota in autoimmune and immune-mediated dermatological conditions like lupus and psoriasis, but reports no new clinical results; the authors emphasize the need for further study into microbial signatures and treatments.
2 citations
,
July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that oral administration of Thauera sp. strain GDN1 reduced serum androgen levels in male mice by about 50%, suggesting its potential as a probiotic treatment for hyperandrogenism.
39 citations
,
October 2013 in “Plastic and Reconstructive Surgery” In this study, researchers found that intestine-derived human alpha defensin 5 enhances wound healing, reduces bacterial load, and promotes hair growth in murine burn wound beds by increasing LGR stem cell migration.
48 citations
,
May 2018 in “Expert Opinion on Therapeutic Targets” This review discusses how modern lifestyle factors affecting gut health may contribute to Alopecia Areata in genetically predisposed individuals, reporting no new results but suggesting the need for long-term interventions.