TLDR The SNP rs6457452 is linked to a higher risk of alopecia areata in Koreans.
The study investigated the association between the HSPA1B SNP rs6457452 and alopecia areata in the Korean population. The research involved a sample size of 200 individuals, including 100 patients with alopecia areata and 100 healthy controls. The findings suggested a significant association between the SNP rs6457452 and an increased risk of developing alopecia areata. This study contributed to understanding the genetic factors involved in alopecia areata, particularly in the Korean population, and highlighted the potential role of HSPA1B as a genetic marker for susceptibility to this condition.
81 citations,
January 2011 in “Allergology International” Japanese vitiligo patients and their families often have other autoimmune diseases.
717 citations,
June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
18 citations,
June 2010 in “Cell Stress and Chaperones” Heat treatment increases hair loss in certain mice.
69 citations,
May 2009 in “Journal of Investigative Dermatology” Stress might contribute to hair loss in alopecia areata.
36 citations,
July 2007 in “Journal of Investigative Dermatology” Certain HLA class II alleles increase or decrease the risk of alopecia areata.
185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
1 citations,
June 2023 in “Genes” Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
4 citations,
October 2022 in “Genes” Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.
September 2023 in “Medicina-lithuania” The study suggests that analyzing DNA can help treat hair loss, but more research is needed.
November 2023 in “Scientific Reports” A gene mutation in Lama3 is linked to a common type of hair loss.
6 citations,
November 2019 in “The application of clinical genetics” The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.