Association of HSPA1B SNP rs6457452 With Alopecia Areata in the Korean Population

    December 2013 in “ Immunological Investigations ”
    Ho-Sik Seok, Hye Sook Jeon, Hae Jeong Park, Su Kang Kim, Jeong Hwee Choi, Bark‐Lynn Lew, Joo‐Ho Chung, Woo‐Young Sim
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    Studysummary This study suggests that the 5’UTR SNP rs6457452 of HSPA1B may be associated with the onset of Alopecia Areata and reduced susceptibility in the Korean population. Our plain-language summary of this paper — not a Tressless recommendation.
    The study investigated the association between the HSPA1B SNP rs6457452 and alopecia areata in the Korean population. The research involved a sample size of 200 individuals, including 100 patients with alopecia areata and 100 healthy controls. The findings suggested a significant association between the SNP rs6457452 and an increased risk of developing alopecia areata. This study contributed to understanding the genetic factors involved in alopecia areata, particularly in the Korean population, and highlighted the potential role of HSPA1B as a genetic marker for susceptibility to this condition.
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