Generalized Vitiligo Associated Autoimmune Diseases in Japanese Patients and Their Families

    January 2011 in “ Allergology International
    Tomohiko Narita, Naoki Oiso, Kazuyoshi Fukai, Kenji Kabashima, Akira Kawada, Tamio Suzuki
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    Studysummary Among Japanese patients with generalized vitiligo, this study found a genetic susceptibility to autoimmune diseases, particularly autoimmune thyroid disease, within families.
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    The study investigated the occurrence of autoimmune diseases in 133 Japanese patients with generalized vitiligo and their families. It found that 20.3% of the patients had autoimmune diseases, with autoimmune thyroid disease (12%) and alopecia areata (5.3%) being the most common. Additionally, 26.3% had a family history of generalized vitiligo and/or other autoimmune diseases. The findings suggested a genetically determined susceptibility to both vitiligo and other autoimmune disorders among Japanese vitiligo patients.
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