Histologic Features of Alopecias–Part I: Nonscarring Alopecias

    February 2015 in “ Actas Dermo-Sifiliográficas
    C. Bernárdez, A.M. Molina-Ruiz, Luis Requena
    Image of study
    TLDR The document concludes that recognizing specific histological features of different nonscarring alopecias is crucial for accurate diagnosis and understanding hair loss progression.
    The document from 2015 reviews the histological features of various nonscarring alopecias, which are hair loss conditions where the hair follicles remain intact and can potentially regrow hair. It highlights the importance of understanding the hair cycle and the morphological changes in hair follicles, as alopecias often affect specific phases, especially the anagen phase. The review details key histopathological features for diagnosing different nonscarring alopecias, such as androgenic alopecia, characterized by follicle miniaturization and debated inflammatory infiltrate, and telogen effluvium, marked by a high number of telogen phase follicles. Chronic telogen effluvium, alopecia areata, syphilitic alopecia, trichotillomania, and traction alopecia are also discussed, each with distinct histological features that aid in diagnosis. Traction alopecia, in particular, is characterized by a decrease in terminal hair follicles without inflammatory infiltrate, and can progress to an irreversible stage with fibrosis. The document underscores the necessity of correlating clinical and pathological findings for accurate diagnosis and understanding the progression of these conditions.
    Discuss this study in the Community →

    Research cited in this study

    28 / 28 results

    Related Community Posts Join

    6 / 12 results

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community How is there still no consensus on Topical Dutasteride in 2024?

      in Finasteride/Dutasteride  149 upvotes 6 months ago
      The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

      community Topical Minoxidil is a pain in the ass for diffuse thinners

      in Minoxidil  95 upvotes 1 year ago
      Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Similar Research

    5 / 1000+ results