Alopecia Areata and the Gut: The Link Opens Up for Novel Therapeutic Interventions

    May 2018 in “ Expert Opinion on Therapeutic Targets ”
    Annika Borde, Annika Åstrand
    Studysummary This review discusses how modern lifestyle factors affecting gut health may contribute to Alopecia Areata in genetically predisposed individuals, reporting no new results but suggesting the need for long-term interventions.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm Advances in Therapy · 2017
    2. The Changing Landscape of Alopecia Areata: The Translational Landscape Advances in Therapy · 2017
    3. Mechanisms of Tolerance and Potential Therapeutic Interventions in Alopecia Areata Pharmacology & therapeutics · 2017
    4. Gut Microbiota Plays a Role in the Development of Alopecia Areata Journal of Investigative Dermatology · 2017
    5. Hair Loss Induced by Tumor Necrosis Factor Alpha Inhibitors Journal of clinical and investigative dermatology · 2014
    6. Tolerance Induction by Hair-Specific Keratins in Murine Alopecia Areata Journal of Leukocyte Biology · 2013
    7. Genetic Basis of Alopecia Areata Dermatologic clinics · 2012
    8. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    9. Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions Journal of Dermatological Science · 2010
    10. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    11. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    12. Treatment of Alopecia Areata with Anti-Interferon-Gamma Antibodies Journal of Investigative Dermatology Symposium Proceedings · 2005
    13. Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata Journal of Investigative Dermatology · 2002
    14. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019