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research Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice

18 citations , April 2013 in “PLOS ONE”

This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.

research Autoimmune Hair Loss Induced by Alloantigen in C57BL/6 Mice.

3 citations , January 2003 in “Cell Structure and Function”

This study found that Meth-A cells induced alopecia in mice, but this effect was blocked by a protein kinase inhibitor, suggesting immunological mechanisms involving lymphokine-activated killer cells.

research Hair Texture Changes and Regeneration after Chemotherapy may Lead us to Treat Autoimmune Hair Loss

September 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

This review explores the possibility of using the side effects of chemotherapeutic agents for regenerating hair follicles, potentially offering a new treatment avenue for different types of alopecia.

research Autoimmune Disease and Hair Loss

35 citations , October 2012 in “Dermatologic Clinics”

This article reviews the impact of different forms of alopecia on patients with systemic autoimmune diseases and reports no new clinical findings; it emphasizes the need for attentive management of alopecia-related symptoms.

research Artificial neural networks algorithms for prediction of human hair loss related autoimmune disorder problem

5 citations , July 2023 in “Journal of Autonomous Intelligence”

This study evaluates a framework using neural networks and machine learning techniques to classify and detect Alopecia Areata from hair images, aiming for accurate differentiation between healthy hair and the condition.

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learn Tofacitinib

JAK inhibitor pill, an immune-system drug

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.
What are the key limitations and considerations surrounding tofacitinib in hair loss products and therapies? Reported hair regrowth with tofacitinib comes from alopecia areata, an autoimmune condition — mostly from small, non-randomized studies, with relapse common after stopping. There is no good evidence it helps pattern hair loss, and it is not approved for hair loss anywhere.

learn Baicapil

Patchy hair loss or alopecia areata: is there any evidence for Baicapil? There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts; none of it involved people with autoimmune patchy hair loss.

learn Baricitinib

JAK inhibitor pill used for severe alopecia areata

Can Baricitinib work if my hair loss is from stress or anxiety? Baricitinib is approved for severe alopecia areata in adults, an autoimmune condition. It has not been shown to work for stress-related shedding (telogen effluvium) and carries an FDA boxed warning.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and there is no evidence that salicylic acid helps hair regrow in it.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Neem Oil

Oil from the neem tree, used in traditional remedies

Community Join

5 / 216 results

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Dutasteride thins eyebrows and facial hair but doesn't stop scalp loss.

in Finasteride/Dutasteride 37 upvotes 1 year ago

Dutasteride may not effectively stop scalp hair loss and can cause thinning of facial and body hair, including eyebrows. Users suggest considering other causes like autoimmune conditions or vitamin deficiencies and exploring treatments like finasteride or minoxidil.

community My 15+ Year Hair Loss Journey: DUPA, Recurrent Alopecia Areata, & different dosages of Min / Fin topicals - Advice needed on next steps.

4 upvotes 3 weeks ago

The user has been managing hair loss for over 15 years, using treatments like Minoxidil, Finasteride, and corticosteroids, while experiencing side effects and recurrent Alopecia Areata. They seek advice on progression and potential underlying conditions, questioning if their hair loss is due to an autoimmune issue beyond typical patterns.

community is there anything that stops hair loss?

8 upvotes 1 year ago

A user is experiencing rapid hair loss and has been diagnosed with telogen effluvium by multiple dermatologists, but doubts the diagnosis due to the severity and speed of the hair loss. They are considering various treatments like spironolactone, estradiol, and possibly finasteride, while also exploring the possibility of hormonal imbalances or autoimmune issues.

community Hair deteriorated in 8 months fin+min.

5 upvotes 2 weeks ago

The user experienced worsening hair loss after 8 months of using finasteride and minoxidil, with no initial shedding or improvement. Suggestions included checking for autoimmune issues, thyroid problems, and consulting a dermatologist.

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