Alopecia Areata: Review of Epidemiology, Pathophysiology, Current Treatments and Nanoparticulate Delivery System

March 2024 in “ Therapeutic Delivery ”

Robel Singh, Pawan Kumar, Davinder Kumar, Navidha Aggarwal, Hitesh Chopra, Virender Kumar

alopecia areata autoimmune condition nonscarring hair loss hair follicles topical treatments systemic treatments injectable treatments nanoparticulate drug-delivery systems

TLDR Nanoparticle drug delivery could improve alopecia areata treatment.

Alopecia areata (AA) is an autoimmune condition characterized by nonscarring hair loss in round patches, affecting both hair follicles and nails. It can occur at any age and presents a complex challenge for treatment. This review discusses the epidemiology, clinical features, and pathogenesis of AA, focusing on current therapies such as topical, systemic, and injectable treatments. A significant emphasis is placed on the potential of nanoparticulate drug-delivery systems to improve the effectiveness and precision of therapeutic agents, aiming to enhance treatment outcomes for those affected by AA.

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