Exploring the Effects of Chinese Herbal Ingredients on the Signaling Pathway of Alopecia and Screening Effective Compounds

April 2022 in “ Journal of Ethnopharmacology ”

Dou Jinjin, Zhang Zhi-Ming, Xu Xianrong, Zhang Xiwu

Chinese herbal ingredients alopecia hair loss traditional Chinese medicine glycoside active ingredients hair follicle cells anagen phase apoptosis hair growth-promoting factors TCM hair regrowth

Studysummary This review discusses the therapeutic mechanisms of Traditional Chinese Medicine in treating alopecia but reports no new clinical results; the authors emphasize the need for more guided clinical application and research on herbal combinations.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document reviews the effects of Chinese herbal ingredients on the signaling pathway of alopecia and screens effective herbal compounds for treating hair loss. Alopecia, or hair loss, is a condition that can be caused by various factors, including genetics, diet, alcohol abuse, and mental stress. The study highlights that traditional Chinese medicine (TCM), particularly those with glycoside active ingredients, has shown efficacy in preventing and treating hair loss and promoting hair regrowth. The research direction of Chinese medicine is mainly to promote the early entry of hair follicle cells into the anagen phase or to inhibit the apoptosis of hair follicle cells. The paper concludes that Chinese herbal medicine treats hair loss by targeting and regulating hair growth-promoting factors and preventing apoptosis, thus maintaining the dynamic balance between hair growth and hair loss.

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