Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis
February 2022
in “
Stem cell reviews and reports
”
skin epithelial cells adult stem cells epidermis wound healing tumorigenesis interfollicular epidermis pilosebaceous unit multipotent embryonic progenitor keratinocytes cellular plasticity de novo hair follicle formation hair follicle stem cells basal cell carcinoma regenerative medicine hair disorders chronic ulcers skin cells stem cells skin wound repair cancer development skin surface hair and oil gland unit embryonic skin cells cell flexibility new hair follicle formation hair stem cells BCC regenerative treatments hair loss conditions persistent ulcers
Studysummary This review discusses the heterogeneity and plasticity of epithelial stem cells in skin homeostasis, wound healing, and tumorigenesis, reporting no new results but emphasizing the need for further exploration of key regulatory mechanisms.
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