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    Tracing the Cellular Origin of Cancer

    January 2013 in “ Nature Cell Biology ”
    Cédric Blanpain
    Studysummary Understanding where cancer cells come from helps create better prevention and treatment methods.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    2. A Keratin 15 Containing Stem Cell Population From the Hair Follicle Contributes to Squamous Papilloma Development in the Mouse Molecular Carcinogenesis · 2012
    3. Distinct Stem Cells Contribute to Mammary Gland Development and Maintenance Nature · 2011
    4. Basal Cell Carcinomas in Mice Arise from Hair Follicle Stem Cells and Multiple Epithelial Progenitor Populations Journal of Clinical Investigation · 2011
    5. Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma Nature Cell Biology · 2010
    6. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    7. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    8. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    9. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006
    10. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    11. Induction of Basal Cell Carcinomas and Trichoepitheliomas in Mice Overexpressing GLI-1 Proceedings of the National Academy of Sciences · 2000
    12. The Malignant Capacity of Skin Tumors Induced by Expression of a Mutant H-Ras Transgene Depends on the Cell Type Targeted Current Biology · 1998