Search

for
Search:

Glossary Interfollicular Epidermis

outer skin layer between hair follicles

The interfollicular epidermis is the part of the skin's outer layer that exists between hair follicles. It plays a crucial role in protecting the body from environmental damage, preventing water loss, and serving as a barrier against pathogens. This area is composed of multiple layers of cells, including keratinocytes, which are responsible for producing keratin, a protein that strengthens the skin.

Related Terms

Research

5 / 1000+ results

research Type XVII collagen coordinates proliferation in the interfollicular epidermis

124 citations , July 2017 in “eLife”

This study found that COL17 deficiency in neonatal mice causes abnormal skin cell proliferation due to disrupted Wnt signaling, while replenishing or overexpressing COL17 can reverse this effect in both neonatal and aged skin.

research α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis

45 citations , May 2003 in “Journal of Cell Science”

This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.

research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis

14 citations , March 2015 in “Stem Cell Research & Therapy”

This study indicates that ABCG2 expression identifies interfollicular keratinocyte progenitor cells in human epidermis and suggests it could help enrich these stem cells for research and treatment.

research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis

7 citations , August 2020 in “Genes”

This study mapped gene expression in different skin structures of dogs, finding similarities to humans that support using dogs as models for human skin diseases.

View more "interfollicular epidermis" in research →

Community Join

2 / 1000+ results

community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

135 upvotes 1 year ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

View more "interfollicular epidermis" in community →

Learn

1 / 801 results

learn Follicusan

View more "interfollicular epidermis" in learn →

Clinics

1 / 5 results

22
SMP
Maison EpidermisOrléans · FR

Experts

— no results

Try a deeper search in experts →