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    Glossary Interfollicular Epidermis

    outer skin layer between hair follicles

    The interfollicular epidermis is the part of the skin's outer layer that exists between hair follicles. It plays a crucial role in protecting the body from environmental damage, preventing water loss, and serving as a barrier against pathogens. This area is composed of multiple layers of cells, including keratinocytes, which are responsible for producing keratin, a protein that strengthens the skin.

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    1. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    2. α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis Journal of Cell Science · 2003 · 45 citations
    3. Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis Stem Cell Research & Therapy · 2015 · 14 citations
    4. Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis Journal of Investigative Dermatology · 2004 · 10 citations
    5. Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis Genes · 2020 · 7 citations
    6. Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide Journal of Investigative Dermatology · 2007 · 2 citations
    7. Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis JCI Insight · 2025 · 1 citations
    8. Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration International Journal of Molecular Sciences · 2026
    9. 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor Journal of Investigative Dermatology · 2022
    10. Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
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