Biofabrication Technologies in Hair Neoformation

January 2022 in “ Stem cell biology and regenerative medicine ”

Carla M. Abreu, Luca Gasperini, Alexandra P. Marques

TLDR New biofabrication technologies could lead to treatments for hair loss.

The document "Biofabrication Technologies in Hair Neoformation" discusses the potential of biofabrication technologies in hair regeneration. It emphasizes the role of dermal papilla cells in hair growth and the enhancement of their hair-inductive capacity through three-dimensional culture. The paper explores the use of bioengineered hair follicular units, organoid models of dermal papilla, and extracellular matrix hydrogel from human placenta for hair follicle regeneration. It also discusses the potential of 3D bioprinting in creating functional tissue models for personalized drug screening and disease modeling. Additionally, it mentions the use of microencapsulation techniques and laser-assisted biofabrication in tissue engineering. The document concludes that these technologies could potentially create a functional niche for hair follicle stem cells, leading to new treatments for hair loss and alopecia.

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