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research Skin organoids: A new human model for developmental and translational research

31 citations , January 2021 in “Experimental Dermatology”

This review discusses recent advancements in generating appendage-bearing skin organoids from pluripotent stem cells and their potential applications in dermatological research, but reports no new clinical results.

research Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research

April 2026 in “Journal of Dermatological Science”

This study highlights that hair-bearing organoids derived from embryonic stem cells can effectively model androgenic alopecia conditions and test the efficacy of anti-hair loss treatments.

research Microtechnology-based methods for organoid models

223 citations , October 2020 in “Microsystems & Nanoengineering”

This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.

research Establishment of an in vitro organoid model of dermal papilla of human hair follicle

44 citations , June 2018 in “Journal of Cellular Physiology”

This study found that using 3D dermal papilla spheroid models enhances extracellular matrix production and hair follicle marker expression, providing insights into hair follicle biology and potential for drug screening.

research A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection Studies

8 citations , September 2023 in “International Journal of Nanomedicine”

In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.

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community Hair and normal skin created from human pluripotent stem cells for the first time

86 upvotes 6 years ago

Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.

community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results

in Update 415 upvotes 1 year ago

ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 2 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

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