Controlled Rigidity Nanolipogel-Mediated Topical Delivery of Fucosterol for Treating Androgenic Alopecia Through Follicle Targeting, Promoting Angiogenesis and Inhibiting Inflammation

    January 2026 in “ Biomacromolecules ”
    Gaodan Liu, Baihui Guo, Yang Pu … Simin Feng
    Studysummary This study reports that a novel nanolipogel with moderate rigidity (NLG-2.5) enhances transdermal delivery of fucosterol, displaying superior permeability, targeting hair follicles, and promoting hair growth in androgenetic alopecia model mice by inhibiting inflammation and androgen pathways and promoting angiogenesis.
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