Multifunctional Ionic Liquids-Mediated Topical Delivery of Minoxidil and EGCG for Treating Androgenic Alopecia Through Promoting Angiogenesis and Scavenging ROS

    May 2024 in “ Chemical engineering journal ”
    Qian Luo, Jiao Zhang, Samira Batur, Chuansheng Fu, Wei Chen, Qi Xie, Conglian Yang, Zhiping Zhang
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    TLDR New treatment using Minoxidil and EGCG with ionic liquids improves hair growth and quality for hair loss.
    The study presents a novel treatment for Androgenetic Alopecia (AGA) using a combination of Minoxidil (MXD) and Epigallocatechin gallate (EGCG) delivered through multifunctional ionic liquids (ILs) comprising choline and geranic acid (CGIL). The ILs-based drug delivery system was found to improve the efficiency of delivering MXD and EGCG into the skin, overcoming the skin stratum corneum (SC) barrier. The combined treatment of MXD and EGCG was found to regulate oxidative stress and promote vascularization around hair follicles, thus reshaping the microenvironment for efficient AGA treatment. Compared to commercially available minoxidil, the new treatment facilitated a faster transition of hair follicles from the telogen phase to the anagen phase with a lower dose and frequency of administration. The regenerated hair coverage and quality were also better in the group treated with the new formulation.
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       23 upvotes 5 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

      community Natural Remedies: Polyphenols and Hair Loss

       21 upvotes 5 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Should I add oral minoxidil right now?

      in Minoxidil  85 upvotes 6 days ago
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      in Minoxidil  103 upvotes 1 week ago
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