The Role of Oxidative Stress in Early-Onset Androgenetic Alopecia

    December 2016 in “ Journal of Cosmetic Dermatology ”
    Hilal Kaya Erdoğan, Isil Bulur, Evin Kocatürk, Bahadir Yildiz, Zeynep Nurhan Saraçoğlu, Ozkan Alatas
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    TLDR Oxidative stress increases in early hair loss, and family history plays a role; antioxidants may help future treatments.
    This study investigated the role of oxidative stress in early-onset androgenetic alopecia (AGA) in male patients. The study found that there was increased oxidative stress in younger patients with early-onset AGA and that family history is associated with early-onset AGA. The authors suggest that further molecular and genetic studies are needed to investigate the relationship between oxidative stress and AGA etiopathogenesis. They also suggest that topical or systemic antioxidants could be promising in the future treatment of AGA.
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