Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia

    May 2024 in “ Nano letters ”
    Wenli Yang, Yudie Lv, Beibei Wang … Xiangdong Kong
    Studysummary This study developed a quercetin-encapsulated and polydopamine-integrated nanosystem that reshapes the perifollicular microenvironment, showing potential for rescuing hair follicle viability and regenerating hair follicles in androgenic alopecia by scavenging reactive oxygen species and promoting angiogenesis.
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    Research cited in this study 21

    1. ISX9 Loaded Thermoresponsive Nanoparticles for Hair Follicle Regrowth Materials Today Bio · 2023
    2. Nitric Oxide Synergizes Minoxidil Delivered by Transdermal Hyaluronic Acid Liposomes for Multimodal Androgenetic Alopecia Therapy Bioactive Materials · 2023
    3. Androgenetic Alopecia: An Update JAAD International · 2023
    4. Dissolving Microneedle Patch Integrated With Microspheres For Long-Acting Hair Regrowth Therapy ACS Applied Materials & Interfaces · 2023
    5. A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch Bioactive Materials · 2022
    6. Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature Regenerative Therapy · 2022
    7. Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia Nano Letters · 2022
    8. Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model Acta Biomaterialia · 2022
    9. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    10. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021
    11. Hair Transplantation: Basic Overview Journal of The American Academy of Dermatology · 2021
    12. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020
    13. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    14. Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy Biomaterials · 2019
    15. A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth ACS nano · 2019
    16. New Treatments for Hair Loss Actas Dermo-Sifiliográficas · 2017
    17. Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition Journal of Investigative Dermatology · 2016
    18. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    19. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    20. Contemporary Hair Transplantation Dermatologic Surgery · 2009
    21. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005