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Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice

research Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice

7 citations, February 2023 in “Inflammation and Regeneration”

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

Green Fabrication of Seedbed-Like Flammulina Velutipes Polysaccharides-Derived Scaffolds Accelerating Full-Thickness Skin Wound Healing Accompanied by Hair Follicle Regeneration

research Green Fabrication of Seedbed-Like Flammulina Velutipes Polysaccharides-Derived Scaffolds Accelerating Full-Thickness Skin Wound Healing Accompanied by Hair Follicle Regeneration

14 citations, November 2020 in “International Journal of Biological Macromolecules”

Mushroom-based scaffolds help heal skin wounds and regrow hair.

research Inflammatory Loops in the Epithelial-Immune Microenvironment of the Skin and Skin Appendages in Chronic Inflammatory Diseases

3 citations, September 2023 in “Frontiers in immunology”

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

research Thyroid Receptor β: A Promising Target for Developing Novel Anti-Androgenetic Alopecia Drugs

May 2024 in “Drug discovery today”

Thyroid receptor β can help develop new drugs to treat hair loss.

research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance

21 citations, December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

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Community Join

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community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 9 months ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community I just want to say Ru58841 saved my life.

in Chat 28 upvotes 1 year ago

A user's experience with hair loss and scalp inflammation, which was alleviated by using RU58841 along with finasteride and dutasteride. A theory of inflammation possibly being a cause of hairloss is also discussed.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 2 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

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