ISX9 Loaded Thermoresponsive Nanoparticles for Hair Follicle Regrowth

    November 2023 in “ Materials Today Bio ”
    Sapna Sayed, Mehdihasan I. Shekh, Jiaxing Song … Desheng Lu
    Studysummary In this study, researchers developed a novel temperature-sensitive biopolymer-based drug delivery system that enhanced the transdermal delivery of ISX9, a neurogenesis inducer, resulting in more effective hair follicle regrowth and signal pathway activation in vivo compared to traditional topical application.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 10

    1. Isoxazole 9 (ISX9), A Small Molecule Targeting Axin, Activates Wnt/β-Catenin Signaling and Promotes Hair Regrowth British Journal of Pharmacology · 2023
    2. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    3. Advances in Chitosan-Based Nanoparticles for Drug Delivery International Journal of Molecular Sciences · 2021
    4. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
    5. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    6. Stimulation of Hair Growth by Small Molecules That Activate Autophagy Cell reports · 2019
    7. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    8. Topical Products for Human Hair Regeneration: A Comparative Study on an Animal Model Annals of Dermatology · 2016
    9. Scratching the Surface of Skin Development Nature · 2007
    10. Cyproterone Acetate for Hirsutism Cochrane library · 2003