Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management

    Fei Liu, Feng Guo, Desheng Liang … Haijun Zhong
    Studysummary This study found that finasteride niosomes may enhance hair follicle drug accumulation and promote hair regeneration in androgenetic alopecia mice more effectively than current finasteride formulations.
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    Research cited in this study 27

    1. Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
    2. Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target Journal of Medicinal Chemistry · 2021
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    6. Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature Journal of Dermatological Treatment · 2020
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    10. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
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    12. Finasteride and Androgenic Alopecia: From Therapeutic Options to Medical Implications Journal of Dermatological Treatment · 2019
    13. Novel Effect of Sildenafil on Hair Growth Biochemical and Biophysical Research Communications · 2018
    14. Finasteride Nano-Transferosomal Gel Formula for Management of Androgenetic Alopecia: Ex Vivo Investigational Approach Drug Design Development and Therapy · 2018
    15. Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia Archives of Dermatological Research · 2018
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    17. Androgens and Androgen Receptor Action in Skin and Hair Follicles Molecular and Cellular Endocrinology · 2017
    18. Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice Molecules · 2017
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    20. Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia Skin Pharmacology and Physiology · 2017
    21. Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study European Journal of Pharmaceutical Sciences · 2016
    22. Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route European journal of pharmaceutics and biopharmaceutics · 2015
    23. A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers International Journal of Clinical Pharmacology and Therapeutics · 2014
    24. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    25. Inhibitory Activities of Puerariae Flos Against Testosterone 5α-Reductase and Its Hair Growth Promotion Activities Journal of Natural Medicines · 2011
    26. In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers Aaps Pharmscitech · 2008
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    Related research 2

    1. Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management Journal of Drug Delivery Science and Technology · 2023
    2. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992