Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study

June 2016 in “ European Journal of Pharmaceutical Sciences ”

Tarek Ahmed, Khalid M. El-Say

finasteride transdermal film skin permeation Box-Behnken design drug permeation parameters sustained release therapeutic efficiency patient compliance Propecia

TLDR Optimized film improves finasteride skin absorption and treatment efficiency.

The study aimed to optimize the formulation of a transdermal film loaded with finasteride microplates to enhance drug skin permeation. The researchers used a Box-Behnken design to investigate the effects of different factors on the film's thickness, elongation percent, and drug permeation parameters. The optimized formulation could provide sustained release of finasteride and enhance its skin permeation. The developed formulation provided gradual release of finasteride from the transdermal film, which could improve therapeutic efficiency and patient compliance.

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research Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study

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Optimized film improves finasteride skin absorption and treatment efficiency.

Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study

Research cited in this study

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