Preparation of Finasteride Capsules-Loaded Drug Nanoparticles: Formulation, Optimization, In Vitro, and Pharmacokinetic Evaluation

This document summarizes several studies that aimed to prepare and evaluate finasteride capsules loaded with drug nanoparticles for improved drug delivery. The studies used various techniques to optimize the formulation and processing variables, resulting in improved solubility, stability, and in vitro dissolution of the drug. The pharmacokinetic studies in animals showed that the optimized nanoparticles had a higher bioavailability compared to the non-nanosized drug. The studies suggest that the use of nanotechnology can enhance the bioavailability and efficacy of finasteride.