Finasteride

    April 1999 in “ Drugs
    Michelle I. Wilde, Karen L. Goa
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    TLDR Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
    Finasteride is a drug used to treat benign prostatic hyperplasia (BPH) by inhibiting the activity of 5α-reductase, which reduces dihydrotestosterone levels. It reduces prostate size, improves urinary flow rates, and symptoms associated with BPH. However, it can cause sexually related adverse events such as impotence and decreased libido. Finasteride is generally well-tolerated and is more cost-effective than other treatments for patients with moderate symptoms who receive the drug for ≤3 years and ≤14 years, respectively. It is recommended for use in men with BPH after excluding prostate cancer and other conditions.
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