Finasteride

    April 1999 in “ Drugs ”
    Michelle I. Wilde, Karen L. Goa
    Studysummary This study concluded that finasteride is a viable first-line treatment for moderate uncomplicated benign prostatic hyperplasia, particularly in patients with larger prostates, by significantly reducing acute urinary retention and the need for surgery.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 18

    1. The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment Among Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1998
    2. Maximum Efficacy of Finasteride Is Obtained Within 6 Months and Maintained Over 6 Years European Urology · 1998
    3. Reversible Severe Myopathy During Treatment with Finasteride Muscle & Nerve · 1997
    4. The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia The New England Journal of Medicine · 1996
    5. Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men The Journal of Clinical Endocrinology and Metabolism · 1996
    6. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996
    7. Identification of Human Cytochrome P450 Isozymes Responsible for the In Vitro Oxidative Metabolism of Finasteride PubMed · 1995
    8. Pharmacodynamic Modeling of Finasteride, a 5 Alpha-Reductase Inhibitor PubMed · 1995
    9. Effect of Finasteride on Adrenal Steroidogenesis in Men PubMed · 1994
    10. Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine The Journal of Clinical Pharmacology · 1993
    11. Finasteride Drugs · 1993
    12. Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor Biochemistry · 1993
    13. Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor Toxicology and Applied Pharmacology · 1993
    14. Prolonged Treatment with Finasteride (a 5α-Reductase Inhibitor) Does Not Affect Bone Density and Metabolism Clinical Endocrinology · 1992
    15. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992
    16. Effects of Long-Term Treatment With Finasteride (MK-906), a 5-Alpha Reductase Inhibitor, on Circulating LH, FSH, Prolactin, and Estradiol Hormone and Metabolic Research · 1992
    17. Disposition and Pharmacokinetics of [14C]Finasteride After Oral Administration in Humans PubMed · 1992
    18. Effects of Flutamide and Finasteride on Rat Testicular Descent Endocrinology · 1991

    Related research 2

    1. Pharmacotherapy of Androgenetic Alopecia – A Literature Review Journal of Education, Health and Sport · 2022
    2. Retracted Article: Interaction Study Between Finasteride and Tamsulosin in Healthy Young Male Subjects Clinical Drug Investigation · 2013