Novel Effect of Sildenafil on Hair Growth

    October 2018 in “ Biochemical and Biophysical Research Communications ”
    Hye In Choi, Bomi Kang, Jaehee Jang … Oh Sang Kwon
    Studysummary In this study, sildenafil was found to enhance human dermal papilla cell proliferation and promote hair growth in mice, suggesting potential use in alopecia treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 12

    1. The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms Journal of Dermatological Science · 2018
    2. A Role of Placental Growth Factor in Hair Growth Journal of dermatological science · 2014
    3. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
    4. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    5. Determination of the Sildenafil Effect on Alopecia Areata in Childhood: An Open-Pilot Comparison Study Journal of Dermatological Treatment · 2006
    6. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    7. Topical Minoxidil Counteracts Stress-Induced Hair Growth Inhibition in Mice Experimental Dermatology · 2003
    8. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    9. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    10. Topical Minoxidil for Hair Regrowth Journal of The American Academy of Dermatology · 1984
    11. Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography Journal of Investigative Dermatology · 1984
    12. Alopecia Areata Treated With Topical Minoxidil Archives of Dermatology · 1984