A Simple Non-Invasive Approach Toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System

    Yulia Svenskaya, Elina A. Genina, Bogdan Parakhonskiy … Gleb B. Sukhorukov
    Studysummary In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.
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    Research cited in this study 19

    1. Skin Permeability and Transdermal Delivery Route of 50-nm Indomethacin-Loaded PLGA Nanoparticles Colloids and Surfaces B: Biointerfaces · 2017
    2. Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8 Scientific reports · 2016
    3. Triggered Release of Model Drug from Gold Nanoparticle-Doped Bovine Serum Albumin Nanocarriers in Hair Follicles Using Infrared A Radiation Acta Biomaterialia · 2015
    4. Hair Follicles as a Target Structure for Nanoparticles Journal of innovative optical health sciences/Journal of innovation in optical health science · 2015
    5. Delivery and Targeting of Nanoparticles into Hair Follicles Therapeutic Delivery · 2014
    6. Quantification of Nanoparticle Uptake Into Hair Follicles in Pig Ear and Human Forearm Journal of Controlled Release · 2014
    7. Drug Delivery to Hair Follicles Expert opinion on drug delivery · 2013
    8. Advanced Chemical Imaging and Comparison of Human and Porcine Hair Follicles for Drug Delivery by Confocal Raman Microscopy Journal of Biomedical Optics · 2012
    9. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    10. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    11. Follicular Transport Route: Research Progress and Future Perspectives European journal of pharmaceutics and biopharmaceutics · 2009
    12. Comparison of Stratum Corneum Penetration and Localization of a Lipophilic Model Drug Applied in an O/W Microemulsion and an Amphiphilic Cream European journal of pharmaceutics and biopharmaceutics · 2007
    13. Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil Journal of Drug Targeting · 2007
    14. Investigation of Differences in Follicular Penetration of Particle- and Nonparticle-Containing Emulsions by Laser Scanning Microscopy Laser Physics · 2006
    15. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    16. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    17. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    18. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    19. Hair Anatomy for the Clinician Journal of The American Academy of Dermatology · 1991