Nanocarrier Systems for Transdermal Drug Delivery

October 2012 in “ InTech eBooks ”

José Juan Escobar-Chávez, Isabel Marlen Rodríguez-Cruz, Clara Luisa Domínguez-Delgado, Roberto Díaz Torres, Alma Revilla-Vázquez, Norma Casas Aléncaster

Studysummary Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on doi.org →

Discuss this study in the Community →

Research cited in this study

6 / 6 results

research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane

211 citations , June 2012

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

research Anatomy and Physiology of the Skin

277 citations , July 2011 in “Journal of the Dermatology Nurses’ Association”

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles

162 citations , August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study introduces a novel non-invasive method called "differential stripping" to quantify the penetration of topically applied substances into hair follicles.

research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin

64 citations , April 2005 in “Journal of Investigative Dermatology”

This study observed that topical oligonucleotide penetration in mouse skin involves a follicular route, suggesting potential suitability for targeting hair follicle-related structures.

research Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles

253 citations , June 2004 in “Journal of Controlled Release”

The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

82 citations , January 2002 in “Journal of drug targeting”

This study found that drug delivery through human scalp skin may be more effective for lipophilic and hydrophilic drugs compared to abdominal skin, highlighting the potential of intrafollicular delivery methods.