Advanced Chemical Imaging and Comparison of Human and Porcine Hair Follicles for Drug Delivery by Confocal Raman Microscopy

    November 2012 in “ Journal of Biomedical Optics ”
    Lutz Franzen, Christiane Mathes, Steffi Hansen, Maike Windbergs
    Studysummary This study used confocal Raman microscopy to confirm optical similarity between human and porcine hair follicles, supporting its use in assessing trans-follicular drug delivery.
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    Research cited in this study 5

    1. Measuring Changes in Chemistry, Composition, and Molecular Structure Within Hair Fibers by Infrared and Raman Spectroscopic Imaging Journal of Biomedical Optics · 2011
    2. Comparison of Artificial Sebum with Human and Hamster Sebum Samples International journal of pharmaceutics · 2008
    3. In Vitro Permeation of Drugs Into Porcine Hair Follicles: Is It Quantitatively Equivalent to Permeation Into Human Hair Follicles? Journal of Pharmacy and Pharmacology · 2008
    4. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    5. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005