TLDR Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.
The document reviews advancements in topical and transdermal drug delivery systems, focusing on nanoformulations. It highlights the potential of nanoparticles to enhance drug delivery efficiency, skin penetration, and therapeutic efficacy for conditions like alopecia, psoriasis, and dermatitis. Notable developments include minoxidil-loaded nanoparticles for hair regrowth and β-sitosterol-loaded cubosomes with microneedles for treating alopecia. These innovations aim to improve drug stability, reduce side effects, and optimize treatment outcomes by targeting specific skin conditions. Despite significant progress, challenges remain in formulating safe and effective nanoparticle-based delivery systems due to skin barrier properties and variability.
November 2023 in “Materials Today Bio” The new treatment using nanoparticles with ISX9 can effectively regrow hair without major side effects.
September 2023 in “Pharmaceuticals” Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” The study created a new hair loss treatment paste that regrows hair faster and with fewer side effects than minoxidil alone.
3 citations
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May 2023 in “International Journal of Molecular Sciences” A new treatment using nanoparticles can effectively prevent and reduce hair loss caused by chemotherapy.
5 citations
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April 2023 in “Bioengineering & Translational Medicine” STAR particles are safe, comfortable, and effective for enhancing drug delivery through the skin.
5 citations
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April 2023 in “Pharmaceuticals” The new delivery system improved hair growth in alopecia treatment.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
35 citations
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June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
182 citations
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December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
