Transferosomes: Unique Vesicular Carriers for Effective Transdermal Delivery
May 2021
in “
Journal of Applied Pharmaceutical Science
”
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Studysummary This review highlights that transferosomes, or ultradeformable lipids, show promise for improving dermal delivery, exhibiting efficient drug transport across the skin's barrier and offering potential benefits for treating chronic skin disorders with better bioavailability. Our plain-language summary of this paper — not a Tressless recommendation.
The document discussed the potential of transferosomes, which are ultradeformable lipids and elastic liposomes, as effective vesicular carriers for transdermal drug delivery. These nanocarriers were highlighted for their ability to overcome the barrier of the stratum corneum, making them suitable for treating chronic skin disorders and ensuring targeted and controlled drug delivery. Transferosomes, composed of edge activators, phospholipids, and buffering agents, demonstrated enhanced elasticity and penetration capabilities, optimizing drug solubilization, loading, and permeability. The document emphasized their secure and efficient delivery strategies for both pharmaceutical and cosmeceutical applications, with recent research showing their reproducible and efficient drug permeation, thus improving bioavailability.
