TLDR Transethosomes improve drug delivery through the skin and show promise for treating various conditions.
The review provides a comprehensive analysis of transethosomes, ultra-deformable vesicular systems that enhance transdermal drug delivery by improving skin penetration, solubility, absorption, and stability of therapeutics. These systems combine the benefits of transferosomes and ethosomes, allowing for the encapsulation of both hydrophilic and hydrophobic drugs, and are applicable in various administration routes, including ophthalmic and transvaginal. Transethosomes have shown promise in treating conditions like psoriasis, skin cancer, and fungal infections, with studies demonstrating improved drug release and therapeutic efficacy. Despite challenges such as stability issues and potential skin irritation, transethosomes offer a versatile and scalable solution for enhanced drug delivery, with ongoing research exploring their broader applications beyond transdermal delivery.
3 citations,
September 2022 in “Journal of Drug Delivery Science and Technology” Minoxidil, a hair loss treatment, works better and has fewer side effects when put into tiny particles called transethosomes, especially those containing oleic acid.
10 citations,
May 2021 in “Expert Opinion on Drug Delivery” Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
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11 citations,
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1 citations,
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1 citations,
January 2023 in “Journal of pharmaceutical and biological sciences” Ethosomes are a promising way to deliver drugs through the skin.
[object Object] 10 citations,
May 2021 in “Expert Opinion on Drug Delivery” Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
222 citations,
January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems” Ethosomes can safely and effectively deliver various drugs deep into the skin.
1 citations,
July 2022 in “Pakistan biomedical journal” Transethosomes improve drug delivery through the skin by overcoming the outer skin layer's barrier.
