Transferosomes Versus Transethosomes for the Dermal Delivery of Minoxidil: Preparation and In Vitro/Ex Vivo Appraisal

    September 2022 in “ Journal of Drug Delivery Science and Technology ”
    Ayat Allam, Dina Fathalla, Mohamed Safwat, Ghareb M. Soliman
    Studysummary This study reported that encapsulating minoxidil in transferosomes and transethosomes can enhance skin permeability and drug retention compared to its conventional formulation, potentially increasing efficacy in androgenic alopecia treatment while reducing side effects, especially when transethosomes contain oleic acid.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Research cited in this study 21

    1. Minoxidil Nanoparticles Targeting Hair Follicles Enhance Hair Growth in C57BL/6 Mice Pharmaceutics · 2022
    2. Nanostructured Lipid Carriers Loaded with Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia European Journal of Pharmaceutics and Biopharmaceutics · 2022
    3. Observations Suggesting a Contribution of Altered Dermal Papilla Mitochondrial Function to Androgenetic Alopecia Experimental Dermatology · 2022
    4. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    5. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    6. Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature Journal of Dermatological Treatment · 2020
    7. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    8. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
    9. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    10. Solubility of Minoxidil in Binary Mixture of Ethanol and Water at Various Temperatures Physics and chemistry of liquids · 2018
    11. Minoxidil-Encapsulated Poly(L-Lactide-Co-Glycolide) Nanoparticles with Hair Follicle Delivery Properties Prepared Using Solvent Evaporation and Sonication Bio-medical Materials and Engineering · 2018
    12. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    13. Solubility of Minoxidil in Methanol, Ethanol, 1-Propanol, 2-Propanol, 1-Butanol, and Water from 278.15 to 333.15 K Journal of Chemical & Engineering Data · 2011
    14. Transcutol-Containing Vesicles for Topical Delivery of Minoxidil Journal of Drug Targeting · 2010
    15. Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil Journal of Drug Targeting · 2007
    16. Effect of Ethosomal Minoxidil on Dermal Delivery and Hair Cycle of C57BL/6 Mice Journal of Dermatological Science · 2006
    17. Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles Journal of controlled release · 2004
    18. Androgenetic Alopecia in Women Journal of Investigative Dermatology Symposium Proceedings · 2003
    19. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    20. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    21. Treatment of Hair Loss The New England Journal of Medicine · 1999

    Related research 1

    1. Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting Pharmaceutics · 2018