TLDR Invasomes with natural terpenes can improve drug delivery through the skin.
The document reviews the use of invasomal carriers, which incorporate natural terpenes, to enhance transdermal drug delivery. The stratum corneum is a significant barrier to drug permeation, and terpenes are recognized as effective permeation enhancers by the FDA. Invasomes, composed of phospholipids, ethanol, and terpenes, offer improved flexibility and permeability, making them a promising approach for transdermal drug delivery. The paper provides an updated overview of the role of terpenes and invasomes in pharmaceutical formulations, highlighting their potential to improve drug permeation through the skin.
35 citations
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January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
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November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
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February 2013 in “Pharmaceutical nanotechnology” Finasteride delivery through skin improved using invasomes and iontophoresis.
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June 2010 in “Australasian Journal of Dermatology” Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.
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July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
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August 2022 in “Scholars academic journal of pharmacy” Invasomes loaded with clotrimazole gel could improve drug delivery through the skin for fungal treatment.
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July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
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July 2015 in “International Journal of Nanomedicine” Increased liposome fluidity boosts skin penetration of sodium fluorescein.
130 citations
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August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
