Formulation, Development and Evaluation of Invasomes Loaded Clotrimazole Gel for Fungal Treatment

The document presents the development of invasomes loaded with clotrimazole gel, aiming to enhance the transdermal delivery of clotrimazole for fungal treatment. Invasomes, which are superior to traditional liposomes in skin permeation, consist of phospholipids, ethanol, and terpenes. The study focused on the formulation process using a mechanical dispersion method and the potential of invasomes in various pharmaceutical applications, such as immunosuppressive drug delivery and treatment for conditions like alopecia, acne, erectile dysfunction, and cancer. Although the document does not provide specific data or the number of subjects, it concludes that invasomes could significantly improve drug delivery through the skin. The research was supported by the Mahakal Institute Of Pharmaceutical Studies.