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research Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways

3 citations , September 2024 in “International Journal of Molecular Sciences”

This review examines how mathematical modeling of the MAPK pathway, enhanced by single-cell proteomic data, improves understanding of regulatory mechanisms, predicts system behavior, and guides experimental research, emphasizing recent developments in modeling and inference.

research Mathematical Modeling of Alopecia Areata: Unraveling Hair Cycle Dynamics, Disease Progression, and Treatment Strategies

January 2024 in “Research Square”

In this study, researchers developed a mathematical model to explore how immune system dynamics affect hair follicle behavior in alopecia areata, identifying key parameters influencing disease progression and suggesting potential treatment strategies targeting immune dysregulation.

research Mathematical Modeling of Alopecia Areata: Unraveling Hair Cycle Dynamics, Disease Progression, and Treatment Strategies

January 2024 in “Applied Mathematics and Nonlinear Sciences”

This study developed a mathematical model to explore the interactions between hair cycle dynamics and immune system activity in alopecia areata, providing insights into disease progression and potential targets for treatment by simulating immune response effects on hair follicles.

research Regenerative medicine meets mathematical modelling: developing symbiotic relationships

25 citations , April 2021 in “npj Regenerative Medicine”

This review highlights the potential role of mathematical and computational approaches in enhancing and accelerating the clinical translation of regenerative medicine products but reports no new clinical findings.

research Increasing the solubility of minoxidil using a mixture of 1-propanol and water by the shake flask method: experimental measurements, thermodynamic analyses, and mathematical modeling

December 2025 in “Brazilian Journal of Chemical Engineering”

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community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 598 upvotes 1 year ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

community Research Backed Dutasteride Simulator (Serum/Scalp DHT included for all doses)

116 upvotes 1 year ago

A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.

community Be careful about using non-PG based alternatives of Minoxidil (mathematically speaking, haven’t seen much practical studies)

in Research/Science 7 upvotes 1 month ago

Minoxidil formulations often use propylene glycol (PG) for stability and effectiveness, but PG-free alternatives like foams and PEG-based solutions can also be effective with less irritation. Concerns exist about the quality of PG-free minoxidil from lesser-known brands, especially from India, due to potential manufacturing issues.

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