Advances in Nanotechnology-Based Topical Delivery Systems for Skincare Applications
January 2026
in “
Pharmaceutics
”
nanotechnology topical delivery systems skincare formulations skin penetration controlled release nanocarrier platforms vesicular nanoparticles lipid-based nanoparticles emulsion-based nanoparticles polymeric nanoparticles inorganic nanoparticles inclusion complexes skin disorders cosmetic solutions cosmetology nano skincare skin delivery systems skin care technology nano carriers nano particles skin treatment
TLDR Nanotechnology in skincare improves ingredient stability, skin penetration, and controlled release for better cosmetic solutions.
The review discusses advancements in nanotechnology-based topical delivery systems for skincare, emphasizing their potential to enhance the effectiveness and safety of cosmetic products. These systems, including vesicular, lipid-based, and polymeric nanocarriers, improve the stability, absorption, and targeted delivery of active ingredients, addressing limitations in traditional skincare treatments for conditions like acne, hyperpigmentation, aging, and hair loss. Nanocarriers such as chitosan-based nanoparticles and nanoemulsions have shown promising results in reducing melanin content and acne lesions, and enhancing drug penetration for hair regrowth. However, safety concerns regarding potential cell damage and inflammation necessitate rigorous toxicity assessments and regulatory oversight. The review highlights the importance of selecting appropriate nanocarrier platforms to optimize skincare outcomes while ensuring consumer safety, and it calls for future research to focus on optimizing nanocarrier design and integrating multifunctional materials.
