Advances In Polymeric Nano-Delivery Systems Targeting Hair Follicles For The Treatment Of Acne

    July 2024 in “ Drug Delivery ”
    Yujing Lei, Wanting Jiang, Cheng Peng … Xinhua Xia
    Studysummary This review discusses how polymer-based nanocarriers can enhance drug delivery targeting hair follicles for acne treatment, focusing on factors affecting this delivery method, combination technologies to improve follicle targeting, and recent advancements in polymer nanodrug-delivery systems.
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    Research cited in this study 25

    1. Thymol-Loaded PLGA Nanoparticles: An Efficient Approach for Acne Treatment Journal of nanobiotechnology · 2021
    2. Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles Colloids and surfaces. B, Biointerfaces · 2021
    3. Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing International Journal of Pharmaceutics · 2021
    4. Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls Bioengineering & translational medicine · 2021
    5. An Updated Review of the Sebaceous Gland and Its Role in Health and Diseases Part 2: Pathophysiological Clinical Disorders of Sebaceous Glands Dermatologic Therapy · 2021
    6. Thiolated and PEGylated Silica Nanoparticle Delivery to Hair Follicles International journal of pharmaceutics · 2020
    7. Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy Journal of Controlled Release · 2020
    8. Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus International Journal of Biological Macromolecules · 2020
    9. Selective Delivery of Adapalene to the Human Hair Follicle Under Finite Dose Conditions Using Polymeric Micelle Nanocarriers Nanoscale · 2017
    10. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    11. Iontophoretic Transdermal Delivery Using Chitosan-Coated PLGA Nanoparticles for Positively Charged Drugs Colloids and surfaces. B, Biointerfaces · 2017
    12. Skin Permeability and Transdermal Delivery Route of 50-nm Indomethacin-Loaded PLGA Nanoparticles Colloids and Surfaces B: Biointerfaces · 2017
    13. Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability Journal of pharmaceutical sciences · 2017
    14. Dendritic Polyglycerol and N-Isopropylacrylamide Based Thermoresponsive Nanogels as Smart Carriers for Controlled Delivery of Drugs Through the Hair Follicle Nanoscale · 2016
    15. Development and Characterization of Polymeric Nanoparticle-Based Formulation of Adapalene for Topical Acne Therapy Nanomedicine · 2016
    16. Mechanistic Study of Decreased Skin Penetration Using a Combination of Sonophoresis with Sodium Fluorescein-Loaded PEGylated Liposomes with D-Limonene International journal of nanomedicine · 2015
    17. Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route European journal of pharmaceutics and biopharmaceutics · 2015
    18. Self-Assembled Polymeric Nanocarriers for the Targeted Delivery of Retinoic Acid to the Hair Follicle Nanoscale · 2015
    19. Polymeric Micelle Nanocarriers for the Cutaneous Delivery of Tacrolimus: A Targeted Approach for the Treatment of Psoriasis Molecular pharmaceutics · 2014
    20. Polymeric Nanoparticles-Embedded Organogel for Roxithromycin Delivery to Hair Follicles European Journal of Pharmaceutics and Biopharmaceutics · 2014
    21. Human Hair Follicle: Reservoir Function and Selective Targeting British Journal of Dermatology · 2011
    22. Novel Micelle Formulations to Increase Cutaneous Bioavailability of Azole Antifungals Journal of controlled release · 2011
    23. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    24. Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells by Hair Follicles and Their Transport in Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    25. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006