Polymeric Micelle Nanocarriers for the Cutaneous Delivery of Tacrolimus: A Targeted Approach for the Treatment of Psoriasis

    July 2014 in “ Molecular pharmaceutics ”
    Maria Lapteva, Karine Mondon, Michael Möller … Yogeshvar N. Kalia
    Studysummary This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.
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    Research cited in this study 6

    1. Penetration and Storage of Particles in Human Skin: Perspectives and Safety Aspects European Journal of Pharmaceutics and Biopharmaceutics · 2011
    2. Novel Micelle Formulations to Increase Cutaneous Bioavailability of Azole Antifungals Journal of controlled release · 2011
    3. Microemulsions as a Surrogate Carrier for Dermal Drug Delivery Drug Development and Industrial Pharmacy · 2008
    4. Evaluation of the Permeability of Hair Growing Ingredient Encapsulated PLGA Nanospheres to Hair Follicles and Their Hair Growing Effects Bioorganic & Medicinal Chemistry Letters · 2007
    5. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    6. Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles Journal of controlled release · 2004