Thiolated and PEGylated Silica Nanoparticle Delivery to Hair Follicles

    Jamila H. Al Mahrooqi, Vitaliy V. Khutoryanskiy, Adrian C. Williams
    Studysummary This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.
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    Research cited in this study 15

    1. Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery Medicines · 2018
    2. Minoxidil-Encapsulated Poly(L-Lactide-Co-Glycolide) Nanoparticles with Hair Follicle Delivery Properties Prepared Using Solvent Evaporation and Sonication Bio-medical Materials and Engineering · 2018
    3. Changing the Shape of Hair with Keratin Peptides RSC Advances · 2017
    4. Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia Skin Pharmacology and Physiology · 2017
    5. Nanocarriers for Optimizing the Balance Between Interfollicular Permeation and Follicular Uptake of Topically Applied Clobetasol to Minimize Adverse Effects Journal of Controlled Release · 2015
    6. Quantification of Nanoparticle Uptake Into Hair Follicles in Pig Ear and Human Forearm Journal of Controlled Release · 2014
    7. Solid Lipid Nanoparticles Suspension Versus Commercial Solutions for Dermal Delivery of Minoxidil International Journal of Pharmaceutics · 2011
    8. Penetration and Storage of Particles in Human Skin: Perspectives and Safety Aspects European Journal of Pharmaceutics and Biopharmaceutics · 2011
    9. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    10. Follicular Transport Route: Research Progress and Future Perspectives European journal of pharmaceutics and biopharmaceutics · 2009
    11. Determination of the Cuticle Thickness of Human and Porcine Hairs and Their Potential Influence on the Penetration of Nanoparticles into the Hair Follicles Journal of Biomedical Optics · 2009
    12. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    13. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    14. Development and Characterization of Minoxidil-Loaded Liposomal System for Delivery to Pilosebaceous Units Journal of Liposome Research · 2004
    15. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004