Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil

    December 2023 in “ Pharmaceutics ”
    Ammara Akhtar, Mohammad Waqas, Arshad Mahmood … Mulazim Hussain Asim
    Studysummary In this study, nanoparticles developed with Minoxidil-loaded thiolated β-CDs showed promise for topical scalp use, as they significantly improved drug retention on hair and displayed no irritation in rabbits.
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    Research cited in this study 11

    1. Thiolated and PEGylated Silica Nanoparticle Delivery to Hair Follicles International journal of pharmaceutics · 2020
    2. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    3. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
    4. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    5. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    6. Reactive Keratin Derivatives: A Promising Strategy for Covalent Binding to Hair Journal of colloid and interface science · 2018
    7. Characterization of Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex in Aqueous Alginate Gel Useful for Alopecia Management: Efficacy Evaluation in Male Rats European Journal of Pharmaceutics and Biopharmaceutics · 2017
    8. Topical Minoxidil Fortified with Finasteride: Maintenance of Hair Density After Replacing Oral Finasteride Indian Dermatology Online Journal · 2015
    9. New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment Drug Development and Industrial Pharmacy · 2014
    10. Niosomes as a Vesicular Carrier for Topical Administration of Minoxidil: Formulation and In Vitro Assessment Drug Delivery and Translational Research · 2013
    11. Minoxidil-Containing Dosage Forms: Skin Retention and After-Rinsing Hair-Growth Promotion Drug Delivery · 2003

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    4. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    5. Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial 2010
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