Preparation and In Vitro Evaluation of Protective Effects of Quercetin-Loaded Solid Lipid Nanoparticles on Human Hair Against UV-B Radiation

The study investigated the protective effects of quercetin-loaded solid lipid nanoparticles (SLN) on human hair against UV-B radiation. Using a solvent-emulsified diffusion method, eight nanoparticle formulations were tested and optimized. Six groups of hair were exposed to UV light for 600 hours, and changes were measured using RMS, peak to valley roughness, FTIR, and protein loss. The optimal formulation demonstrated effective penetration and significantly controlled RMS, reduced roughness, chemical changes, and protein loss, indicating its protective benefits against UV-B radiation.