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Glossary Protein Loss

reduction of protein content in hair, causing weakness and breakage

Protein loss refers to the reduction of protein content in the body, which can occur due to various factors such as poor nutrition, medical conditions, or excessive physical stress. In the context of hair, protein loss can weaken hair strands, making them more prone to breakage and leading to conditions like hair thinning or alopecia. For professionals, understanding the underlying causes of protein loss is crucial for diagnosing and treating related health issues effectively.

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Research

5 / 1000+ results

research Protein loss in human hair from combination straightening and coloring treatments

18 citations , July 2015 in “Journal of cosmetic dermatology”

This study observed that combining hair dyeing with sodium hydroxide relaxers drastically increased protein loss in Caucasian virgin dark brown hair, while ammonium thioglycolate or guanidine hydroxide relaxers caused less damage.

research Protein loss quantification of abraded virgin and abraded bleached hair according to Bradford assay

11 citations , March 2005 in “International Journal of Cosmetic Science”

This study found that the Bradford assay is a sensitive and reproducible alternative to the Lowry test for quantifying hair protein loss during brushing, with bleached hair releasing more protein than virgin hair.

research Argan oil as a pretreatment of human hair before exposure to oxidative damage: Attenuated total reflectance and protein loss studies

February 2022 in “Journal of Cosmetic Dermatology”

This study found that pre-treating hair with argan oil reduced protein loss and provided protection against oxidative damage, supported by both ATR spectrum analysis and protein measurements.

research Sensitive method using protein loss measurements to evaluate chemicalperm damage to human hair restoration by shampoo

January 2002 in “China Surfactant Detergent & Cosmetics”

This study compared shampoos and found that shampoo D, containing polyquaternium-10, guar gum, and dimethicone, was most effective in restoring chemically permed hair.

research Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.

26 citations , June 2003 in “PubMed”

In this study, severe hair loss occurred in PKC epsilon transgenic mice treated with DFMO during skin tumor prevention, highlighting a link between polyamine biosynthesis, hair follicle maintenance, and metastasis suppression.

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Community Join

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community Vegan Protein Powder Make Loss Worse?

in Female 2 upvotes 2 years ago

A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

community Whey protein and hair loss

6 upvotes 9 years ago

Whey protein does not cause hair loss; concerns are likely unfounded. The user is on finasteride and minoxidil but sees no improvement, so they are phasing out these treatments while continuing to work out and use whey protein.

community Creatine / Whey Protein / Finasteride Hair Loss?

6 upvotes 2 years ago

A 37-year-old with a receding hairline started using finasteride and plans to add minoxidil, concerned that creatine and whey protein might accelerate hair loss. Another user suggests these supplements likely don't increase testosterone or cause hair loss, advising to monitor personal experience.

community Derm told me that my whey protein usage is speeding up hair loss?

26 upvotes 5 months ago

Whey protein is unlikely to cause hair loss, and some users suggest it might be beneficial if dietary protein is insufficient. Hair loss is generally considered genetic, and there is skepticism about the dermatologist's advice to switch from whey protein to whole foods.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Follistatin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which in laboratory and animal work is described as keeping hair follicles in their growth phase; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Overview

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Stem Cell Factor

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Clinics

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