Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells

    September 2022 in “ Molecules
    Ling Ma, Huchi Shen, Chengge Fang, Timson Chen, Jing Wang
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    TLDR Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
    The study found that Camellia Seed Cake Extract (CSCE) can potentially treat Androgenetic Alopecia (AGA) by counteracting the effects of Dihydrotestosterone (DHT) in human Dermal Papilla Cells (DPCs). CSCE was observed to restore DHT-induced cell damage, reduce inflammatory factors IL-6 and IL-1α, and exhibit anti-apoptotic and anti-androgenic activities. It also inhibited β-galactosidase enzyme activity, slowing down DHT-induced cellular senescence. However, further research is needed to confirm the preventive and therapeutic effects of CSCE on AGA.
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